17  Feasibility & Site Selection

17.1 Goal

Identify sites capable of conducting the trial effectively and in compliance with protocol requirements.

17.2 Feasibility Assessment Domains

  • Patient population
  • Investigator experience
  • Staff availability
  • Facilities and equipment
  • Competing trials
  • Recruitment timelines

17.3 CRA Role

  • Review feasibility questionnaires
  • Participate in site qualification visits (as applicable)
  • Identify potential risks or capacity gaps
NoteOncology-Specific Considerations
  • Access to eligible patient population by tumor type/stage
  • Availability of imaging and central lab workflows
  • Experience with complex protocols and amendments
NoteVaccine Trial Considerations
  • Access to large eligible populations to support rapid enrollment targets.
  • Demonstrated ability to recruit healthy volunteers or target populations efficiently.
  • Capacity to manage high visit volume and protocol-driven vaccination schedules.
  • Experience with vaccine storage, handling, and cold-chain requirements where applicable.