60  Pre-Inspection Preparation

60.1 CRA Pre-Inspection Checklist

60.2 Document Consistency Checks

Verify consistency between: - Source documents - EDC - Monitoring reports - TMF - Correspondence

NoteOncology-Specific Considerations
  • Imaging data and tumor assessments often reviewed
  • Dose modifications scrutinized
NoteVaccine Trial Considerations
  • Specimen collection timing, handling, and laboratory documentation are often reviewed to ensure validity of immunogenicity endpoints.
  • Vaccine accountability, storage conditions, and temperature monitoring records may receive focused inspection review.
  • Documentation supporting vaccination timing and follow-up visit windows should be complete and consistent with protocol requirements.